RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
SIRT2
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
RT-PCR; Western Blot; Immunofluorescence etc.
Target
Smad2; Smad3
Pathway
Smad2/3 pathway
PubMed ID
Title
Inhibition of Sirt2 Alleviates Fibroblasts Activation and Pulmonary Fibrosis?via?Smad2/3 Pathway
Year
2021
Function
Sirt2 expression was upregulated in transforming growth factor-beta1 (TGF-beta1) treated human embryonic lung fibroblasts.